Reid H W, Buxton D, Finlayson I P
Vet Rec. 1981 Jun 6;108(23):497-8. doi: 10.1136/vr.108.23.497.
The response of six calves to subcutaneous inoculation with louping-ill virus was studied. All developed viraemia of low intensity which lasted two to four days followed by the appearance of haemagglutination inhibiting serum antibody. IgM was the predominant class of antibody until day 14. Only one calf developed clinical signs; following a brief period of incoordination on day 7 it became recumbent and was killed on day 12. Severe meningoencephalitis was detected in this calf and mild changes were observed in one of the five survivors which were killed on day 14 or 20. These findings are discussed in relation to the epidemiology of louping-ill and the diagnosis of the disease in cattle.
研究了六头小牛对皮下接种跳跃病病毒的反应。所有小牛都出现了低强度病毒血症，持续两到四天，随后出现血凝抑制血清抗体。直到第14天，IgM是主要的抗体类别。只有一头小牛出现临床症状；在第7天出现短暂的共济失调后，它变得卧地不起，并于第12天被处死。在这头小牛中检测到严重的脑膜脑炎，在第14天或第20天被处死的五头存活小牛中的一头观察到轻微变化。结合跳跃病的流行病学和牛病的诊断对这些发现进行了讨论。
