Schwartz E, Vincúrová M, Martis R, Skutilová L, Rajecová E, Knappková H
Zentralbl Bakteriol Mikrobiol Hyg A Med Mikrobiol Infekt Parasitol. 1981 Sep;250(3):330-42.
The bacterial activity of sera from 116 patients suffering from various forms of tuberculosis of the lung, pleuritis exsudativa, neoplasm of the lung and histologically verified sarcoidosis of the lung were tested against 12 different strains of mycobacteria. The results obtained were then related to the blood-group of the respective patients. As can be seen from the results, there was a statistically significant difference (p = 0.001) between the values of bacterial activity for patients with (1) positive and negative Tb excretion and (2) patients suffering from an indurative and destructive form of tuberculosis of the lung. In contrast, it was not possible to establish statistically significant differences in the level of bacterial activity in patients with different levels of the i.d. tuberculin reaction (3). In patients with positive Tb excretion (4) and patients with destructive tuberculosis of the lung (5) there were increased levels of bacterial activity for all blood-groups if compared with values for patients with negative Tb excretion or patients suffering from indurative forms of lung tuberculosis. A statistical analysis of all results did not confirm the authors' hypothesis that the elevated incidence of destructive forms of tuberculosis and of bacterial excretion among patients having blood-group "O" could be ascribed to an insufficiency of bacteriostatic activity in the sera of these patients.
对116例患有各种类型肺结核、渗出性胸膜炎、肺部肿瘤以及经组织学证实的肺部结节病患者的血清,针对12种不同的分枝杆菌菌株进行了细菌活性检测。然后将所得结果与各患者的血型相关联。从结果可以看出,(1)结核菌素排泄呈阳性和阴性的患者之间以及(2)患有硬结性和破坏性肺结核的患者之间,细菌活性值存在统计学上的显著差异(p = 0.001)。相比之下,不同结核菌素反应水平的患者(3),其细菌活性水平无法建立统计学上的显著差异。与结核菌素排泄呈阴性的患者或患有硬结性肺结核的患者相比,结核菌素排泄呈阳性的患者(4)以及患有破坏性肺结核的患者(5),所有血型的细菌活性水平均有所升高。对所有结果的统计分析并未证实作者的假设,即血型为“O”的患者中破坏性肺结核和细菌排泄发生率升高可归因于这些患者血清中抑菌活性不足。