Gutsche W, Wohlrabe K, Jungstand W, Fleck W F
Arch Geschwulstforsch. 1981;51(5):398-404.
Lambdamycin, a chromoglycoside antibiotic like chartreusin was found to be very active against leukemias L 1210 and P 388 and moderate effective against melanoma B 16 and Lewis lung carcinoma of mice. It was nearly without any effect when tested on Walker 256 carcinoma of rats. The effectiveness of lambdamycin was compared with that of cyclophosphamide, 5-fluorouracil and 6-mercaptopurine.
发现像黄绿青霉素一样的色糖甙抗生素λ霉素对白血病L 1210和P 388具有很强的活性,对小鼠黑色素瘤B 16和Lewis肺癌有中等疗效。在对大鼠的Walker 256癌进行测试时,它几乎没有任何效果。将λ霉素的疗效与环磷酰胺、5-氟尿嘧啶和6-巯基嘌呤的疗效进行了比较。