Ausina Ruiz V, Verger Garau G, Roig Boronat J L, Sancho Navarro R, Prats Pastor G
Med Clin (Barc). 1981 Sep 25;77(5):216-9.
A case of authochthonous mycetoma with Petriellidium boydii as the causal agent, located in the third distal of the lower left leg is reported. The patient was a 35 year old male without any associated pathology. It is assumed that the infecting organism entered the tissues through a lesion caused a few years previously during a traffic accident. On admittance patient was found to have two fistulas on the upper part of the external malleolus from which pus with small yellow granules measuring 1 to 1.5 mm in diameter discharged. Fungus was repeatedly isolated in pure culture in all media in which is was sown. Mycological study of the isolated fungus and histopathology of the lesion are presented. The fungus proved in vitro to be sensitive to miconazole nitrate with minimal inhibitory concentration and minimal fungicide concentration values of less than 0.1 microgram/ml. The third distal of the peroneal bone was excised and arthrodesis of the ankle practiced as conservative treatment and miconazole administered intravenously, Eighteen months later clinical evolution is satisfactory.
报告了一例由博伊德氏皮内癣菌引起的原发性足菌肿病例,病变位于左小腿远端三分之一处。患者为一名35岁男性,无任何相关病史。据推测,感染源通过几年前交通事故造成的伤口进入组织。入院时发现患者在外踝上部有两个瘘管,从中排出直径为1至1.5毫米的带有小黄颗粒的脓液。在接种的所有培养基中均反复分离出纯培养的真菌。文中呈现了分离真菌的真菌学研究及病变的组织病理学检查。体外试验证明该真菌对硝酸咪康唑敏感,其最小抑菌浓度和最小杀菌浓度值均小于0.1微克/毫升。切除腓骨远端三分之一并实施踝关节融合术作为保守治疗,并静脉注射咪康唑。18个月后临床进展令人满意。