Wiener M W, Vondoenhoff L J, Cohen J
Am J Med. 1982 Jan;72(1):157-60. doi: 10.1016/0002-9343(82)90602-7.
Substantial aortic regurgitation developed in a patient with hypertrophic (obstructive) cardiomyopathy (HCM) who underwent septal myectomy. It was first noted 12 years after surgery. There was no evidence for surgical damage to the valve, subacute bacterial endocarditis, coexisting discrete subaortic stenosis or any other known etiology of aortic incompetence. This experience suggests that aortic regurgitation occasionally may be a late mode of deterioration in surgically treated patients with hypertrophic cardiomyopathy. Possible mechanisms for the development of aortic incompetence in such patients are discussed.
一名肥厚型（梗阻性）心肌病（HCM）患者在接受室间隔心肌切除术后出现了严重的主动脉瓣反流。术后12年首次发现该情况。没有证据表明存在手术对瓣膜的损伤、亚急性细菌性心内膜炎、并存的孤立性主动脉瓣下狭窄或任何其他已知的主动脉瓣关闭不全病因。这一病例提示，主动脉瓣反流偶尔可能是肥厚型心肌病手术治疗患者晚期病情恶化的一种形式。文中讨论了此类患者发生主动脉瓣关闭不全的可能机制。
