[Interactions between vessel wall and blood and their role in developmental and therapy of arterial perfusion disorders (author's transl)].

The dynamic balance between the vessel wall and the systems of the platelets, of coagulation and of the fibrinolysis, termed vessel wall-blood homoiostasis, can be altered in a physiologically suitable way as well as pathologically. A disturbance of the vessel wall-blood homoiostasis is considered the key process of the pathogenesis of all obliterating angiopathies. This view can explain why different risk factors may lead to the same picture of obliterative arteriosclerosis. From this point of view practical consequences for the treatment arise which may - under most favorable circumstances - render a restitution and integrum possible or at least a regression of obliterative processes.