Sung D I, Chang C H, Harisiadis L
Cancer. 1982 Feb 1;49(3):553-5. doi: 10.1002/1097-0142(19820201)49:3<553::aid-cncr2820490326>3.0.co;2-a.
Between 1950 and 1976, 24 patients with cerebellar hemangioblastomas received postoperative radiation therapy. In retrospect, the low-dose radiotherapy that was practiced in the 1950s and early 1960s has been associated with inferior survival rates. Since 1963 and with increased awareness of the effects of radiotherapy, patients receiving high-dose irradiation postoperatively have generally survived longer. Postoperative radiotherapy is used whenever the neoplasm has not been totally excised. This more likely to occur with solid hemangioblastoma and neoplasms arising in the brain stem. In addition, radiotherapy should be used when the tumor recurs after total excision. The recommended dose is in the range of 4500--5000 rads in 4 1/2--5 weeks.
1950年至1976年间,24例小脑成血管细胞瘤患者接受了术后放射治疗。回顾过去,20世纪50年代和60年代初采用的低剂量放疗与较低的生存率相关。自1963年以来,随着对放疗效果认识的提高,术后接受高剂量照射的患者总体存活时间更长。只要肿瘤未完全切除,就会进行术后放疗。这种情况在实体性成血管细胞瘤和脑干肿瘤中更易发生。此外,当肿瘤在全切术后复发时也应使用放疗。推荐剂量为在4.5至5周内给予4500至5000拉德。