1-取代-2-硝基咪唑类化合物的构效关系：分配系数和侧链羟基对体外放射增敏作用的影响 - Suppr | 超能文献

Structure-activity relationships of 1-substituted 2-nitroimidazoles: effect of partition coefficient and side-chain hydroxyl groups on radiosensitization in vitro.

作者信息

Brown D M, Parker E, Brown J M

出版信息

Radiat Res. 1982 Apr;90(1):98-108.

Abstract

摘要

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Structure-activity relationships of 1-substituted 2-nitroimidazoles: effect of partition coefficient and side-chain hydroxyl groups on radiosensitization in vitro.1-取代-2-硝基咪唑类化合物的构效关系：分配系数和侧链羟基对体外放射增敏作用的影响

Radiat Res. 1982 Apr;90(1):98-108.

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The effect of misonidazole as a hypoxic radiosensitizer at low dose.低剂量米索硝唑作为低氧放射增敏剂的作用。

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Factors influencing intracellular uptake and radiosensitization by 2-nitroimidazoles in vitro.体外影响2-硝基咪唑类化合物细胞内摄取及放射增敏作用的因素。

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A rapid-mixing comparison of the mechanisms of radiosensitization by oxygen and misonidazole in CHO cells.对氧和米索硝唑在CHO细胞中放射增敏机制的快速混合比较。

Radiat Res. 1982 Apr;90(1):126-41.

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Effects of oxygen and misonidazole on cell transformation and cell killing in C3H 10T1/2 cells by X rays in vitro.氧气和米索硝唑对X射线体外诱导C3H 10T1/2细胞转化及细胞杀伤的影响。

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Glutathione depletion, radiosensitization, and misonidazole potentiation in hypoxic Chinese hamster ovary cells by buthionine sulfoximine.丁硫氨酸亚砜胺对缺氧的中国仓鼠卵巢细胞的谷胱甘肽耗竭、放射增敏及米索硝唑增效作用

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Electron affinic sensitization. V. Radiosensitization of hypoxic bacteria and mammalian cells in vitro by some nitroimidazoles and nitropyrazoles.亲电子致敏作用。V. 某些硝基咪唑和硝基吡唑对缺氧细菌和哺乳动物细胞的体外放射致敏作用

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Combined radiation-protective and radiation-sensitizing agents: II. Radiosensitivity of hypoxic or aerobic Chinese hamster fibroblasts in the presence of cysteamine and misonidazole: implications for the "oxygen effect" (with appendix on calculation of dose-modifying factors).联合辐射防护剂与辐射增敏剂：II. 半胱胺和米索硝唑存在下缺氧或有氧中国仓鼠成纤维细胞的辐射敏感性：对“氧效应”的影响（附剂量修正因子计算附录）

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Radiat Res. 1980 Jun;82(3):478-86.

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