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大鼠垂体后叶儿茶酚胺水平的昼夜变化

Diurnal variations in rat posterior pituitary catecholamine levels.

作者信息

Barden N, Chevillard C, Saavedra J M

出版信息

Neuroendocrinology. 1982 Feb;34(2):148-50. doi: 10.1159/000123292.

Abstract

Diurnal variations, ranging over a twofold difference in concentrations of dopamine, norepinephrine and epinephrine, occur in the rat posterior pituitary gland during a 24-hour period. Highest catecholamine concentrations were seen during daylight hours and low levels reached a nadir 5 h after the onset of darkness. Dopamine concentrations rapidly returned to high levels at the onset of the daylight period, whilst the increase in norepinephrine and epinephrine concentrations was delayed. These diurnal variations in catecholamine content may reflect their modulation of neural lobe peptide secretion.

摘要

在24小时内,大鼠垂体后叶中多巴胺、去甲肾上腺素和肾上腺素的浓度存在昼夜变化,浓度差异可达两倍。在白天时段观察到儿茶酚胺浓度最高,而在黑暗开始5小时后达到最低点。白天开始时,多巴胺浓度迅速恢复到高水平,而去甲肾上腺素和肾上腺素浓度的增加则延迟。儿茶酚胺含量的这些昼夜变化可能反映了它们对神经叶肽分泌的调节作用。

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