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α-氯醇给药后睾丸-附睾复合体中的磷脂分析。

Phospholipid analysis in testis-epididymis complex after alpha-chlorohydrin administration.

作者信息

Kalla N R, Singh B

出版信息

Contraception. 1978 Jun;17(6):523-30. doi: 10.1016/s0010-7824(78)80003-1.

Abstract

alpha-Chlorohydrin, 6.5 mg/kg body weight for 14 days, did not alter total phospholipids, phosphatidyl choline, phosphatidyl ethanolamine, phosphatidyl serine, phosphatidyl inositol and sphingomyelin in rat testis and caput and corpus epididymis. However, marked decrease in total phospholipids, phosphatidyl choline, phosphatidyl ethanolamine and phosphatidyl inositol in cauda epididymis and vas deferens was observed. p32 incorporation also showed similar changes in phospholipids.

摘要

α-氯醇,以6.5毫克/千克体重的剂量给药14天,并未改变大鼠睾丸、附睾头和附睾体中的总磷脂、磷脂酰胆碱、磷脂酰乙醇胺、磷脂酰丝氨酸、磷脂酰肌醇和鞘磷脂。然而,观察到附睾尾和输精管中的总磷脂、磷脂酰胆碱、磷脂酰乙醇胺和磷脂酰肌醇显著减少。³²P掺入也显示出磷脂的类似变化。

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