Pisarev V B
Probl Endokrinol (Mosk). 1982 Mar-Apr;28(2):60-3.
In the experiments on albino male rats histological and stereological alterations of hypothalamic neurones were studied during long-tern immobilization-pain stress. It was shown, that dissimilar qualitative and quantitative neuronal changes arise in the rat hypothalamus. Significant decrease in neuronal volume density, which is likely to be caused by dystrophy and cell necrosis phenomena, was seen in supraoptic, suprachiasmal, paraventricular, ventral median, dorsal premammillar, supramammillar nuclei and the anterior hypothalamus. Neurones of the ventricular premammillar nucleus were characterized by significant augmentation of volume density, apparently due to cell hypertrophy.
在对白化雄性大鼠进行的实验中，研究了长期制动性疼痛应激期间下丘脑神经元的组织学和体视学改变。结果表明，大鼠下丘脑出现了不同的定性和定量神经元变化。在视上核、视交叉上核、室旁核、腹内侧核、乳头前背核、乳头体上核以及下丘脑前部，观察到神经元体积密度显著降低，这可能是由营养不良和细胞坏死现象引起的。乳头体前脑室旁核的神经元表现为体积密度显著增加，显然是由于细胞肥大所致。
