Hidiroglou M, Williams C J, Hackett A J
Int J Vitam Nutr Res. 1982;52(1):75-9.
Serum levels of copper, iron and zinc were determined throughout complete estrous cycles in 16 ewes. All ewes were normally cycling females exhibiting normal serum progesterone patterns. Copper serum levels tended to be higher during the preovulatory and ovulatory times, presumably due to the transfer of hepatic celuloplasmin as a result of the release of endogenous estrogen. Iron and zinc plasma levels were higher during estrous when the ovarian tissue requirement was higher. It is suggested that the control mechanism responsible for the variations in copper, iron and zinc plasma levels during the estrous cycle may be hormonal in nature.
在16只母羊的整个发情周期中测定了血清铜、铁和锌水平。所有母羊均为正常发情的雌性，血清孕酮水平正常。血清铜水平在排卵前和排卵时往往较高，推测这是由于内源性雌激素释放导致肝铜蓝蛋白转移所致。发情期间，当卵巢组织需求较高时，铁和锌的血浆水平较高。有人认为，发情周期中血浆铜、铁和锌水平变化的控制机制可能本质上是激素性的。
