Sachs C, Sjöberg H E, Ericson K
Neurology. 1982 Jul;32(7):779-82. doi: 10.1212/wnl.32.7.779.
Eleven of 12 patients with primary hypoparathyroidism had CT evidence of bilateral intracerebral calcifications, mostly within the basal ganglia, but also in other sites. None of the 12 patients with secondary hypoparathyroidism had intracerebral calcifications. Among 20 patients with calcifications discovered incidentally, idiopathic hypoparathyroidism was diagnosed in 2 patients. Four patients had calcifications associated with antiepileptic treatment, parkinsonism, or Kearns-Sayre syndrome. The cause of the calcifications was unknown in 14 patients. No specific neurologic sign was related to the localization of the intracerebral calcifications. Incidentally discovered basal ganglia calcifications should lead to endocrinologic evaluation of parathyroid function. CT examination of the skull may be used to ascertain the diagnosis of idiopathic hypoparathyroidism.
12例原发性甲状旁腺功能减退患者中有11例CT显示双侧脑内钙化，主要位于基底节，但也见于其他部位。12例继发性甲状旁腺功能减退患者均无脑内钙化。在偶然发现钙化的20例患者中，2例诊断为特发性甲状旁腺功能减退。4例患者的钙化与抗癫痫治疗、帕金森病或卡恩斯-塞尔综合征有关。14例患者钙化原因不明。没有特定的神经系统体征与脑内钙化的部位相关。偶然发现的基底节钙化应进行甲状旁腺功能的内分泌评估。头颅CT检查可用于确诊特发性甲状旁腺功能减退。
