Zimmerman R A, Bilaniuk L T, Littman P, Raney R B
J Comput Tomogr. 1978 Jun;2(2):113-21. doi: 10.1016/s0149-936x(78)80003-4.
Review of the clinical and roentgenographic findings in 16 children with craniofacial sarcomas has revealed that CT is the most accurate method for delineation of the sarcomas and is indispensable for proper therapy planning and post therapy evaluation. The patients were examined and treated according to a protocol which required a CT examination before any type of therapy and after each mode of therapy, chemotherapy and radiotherapy. Chemotherapy alone was noted to produce marked reduction in tumor volume. The orbital sarcomas, which are most frequent, are small tumors without bone destruction. On the other hand, the nasopharyngeal, paranasal sinus and middle ear sarcomas are large tumors frequently associated with extensive bone destruction.
对16例颅面部肉瘤患儿的临床及X线表现进行回顾后发现，CT是描绘肉瘤最准确的方法，对于合理的治疗计划和治疗后评估必不可少。患者按照一项方案接受检查和治疗，该方案要求在任何类型的治疗前以及每种治疗方式（化疗和放疗）后都进行CT检查。仅化疗就可使肿瘤体积显著缩小。最常见的眼眶肉瘤是无骨质破坏的小肿瘤。另一方面，鼻咽、鼻窦和中耳肉瘤是常伴有广泛骨质破坏的大肿瘤。
