Jacobs A J, Deligdisch L, Deppe G, Cohen C J
Am J Obstet Gynecol. 1982 Jul 1;143(5):574-80. doi: 10.1016/0002-9378(82)90550-6.
The original histologic material of 87 patients with Stage III or IV ovarian adenocarcinoma was reviewed. These patients had been treated with cisplatin, alone or in combination. There was a significant association among the morphologic parameters of histologic differentiation, mitotic activity, and cellular pleomorphism. However, none of these was associated either with survival or with maximum response of the tumor among the cisplatin-treated patients. The possible significance of these findings is discussed.
回顾了87例III期或IV期卵巢腺癌患者的原始组织学材料。这些患者接受了顺铂单药治疗或联合治疗。组织学分化、有丝分裂活性和细胞多形性的形态学参数之间存在显著关联。然而，在接受顺铂治疗的患者中，这些参数均与生存率或肿瘤的最大反应无关。讨论了这些发现的可能意义。
