Gould H J, Caldarelli D D
Arch Otolaryngol. 1982 Jun;108(6):347-9. doi: 10.1001/archotol.1982.00790540019006.
Otologic and audiologic records on patients wit phenotypic characteristics of Apert syndrome were reviewed. Eustachian tube function was evaluated in five patients. The otologic findings indicate that patients with Apert syndrome have serous otitis media and its sequelae develop during infancy, with persistence into adulthood. This situation is analogous to cleft palate and brings to light another form of probable congenital Eustachian tube dysfunction. Stapedial footplate fixation was noted in one patient, and a dehiscent jugular bulb was seen in two others. The middle ear disease contributes to auditory sensory deprivation in the form of a persistent conductive hearing loss.
回顾了具有Apert综合征表型特征患者的耳科和听力学记录。对5名患者的咽鼓管功能进行了评估。耳科检查结果表明，Apert综合征患者在婴儿期会出现浆液性中耳炎及其后遗症，并持续至成年期。这种情况与腭裂类似，揭示了另一种可能的先天性咽鼓管功能障碍形式。在1例患者中发现镫骨足板固定，在另外2例患者中发现颈静脉球裂。中耳疾病以持续性传导性听力损失的形式导致听觉感觉剥夺。
