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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Poston L, Wilkinson S, Sewell R B, Williams R

Clin Sci (Lond). 1982 Sep;63(3):243-9. doi: 10.1042/cs0630243.

Leucocyte sodium transport was investigated as a possible assay for the small molecular weight natriuretic material isolated from the urine of normal subjects who had undergone volume expansion by saline infusion. 2. This fraction (fraction four or FIV), inhibitory to sodium transport in several other assays, was also found to inhibit leucocyte sodium transport. 3. FIV isolated from the urine of five normal subjects undergoing the natriuresis of mineralocorticoid 'escape' was also found to be inhibitory to leucocyte sodium transport. 4. Leucocytes isolated from the blood of the same subjects during mineralocorticoid escape showed decreased sodium transport.

研究了白细胞钠转运，以此作为从经盐水输注扩容的正常受试者尿液中分离出的小分子重量利钠物质的一种可能检测方法。2. 该组分（组分四或FIV）在其他几种检测中对钠转运有抑制作用，也被发现能抑制白细胞钠转运。3. 从经历盐皮质激素“脱逸”性利钠的五名正常受试者尿液中分离出的FIV，也被发现对白细胞钠转运有抑制作用。4. 在盐皮质激素脱逸期间从同一受试者血液中分离出的白细胞显示钠转运减少。

Poston L, Wilkinson S, Sewell R B, Williams R

Clin Sci (Lond). 1982 Sep;63(3):243-9. doi: 10.1042/cs0630243.

Leucocyte sodium transport was investigated as a possible assay for the small molecular weight natriuretic material isolated from the urine of normal subjects who had undergone volume expansion by saline infusion. 2. This fraction (fraction four or FIV), inhibitory to sodium transport in several other assays, was also found to inhibit leucocyte sodium transport. 3. FIV isolated from the urine of five normal subjects undergoing the natriuresis of mineralocorticoid 'escape' was also found to be inhibitory to leucocyte sodium transport. 4. Leucocytes isolated from the blood of the same subjects during mineralocorticoid escape showed decreased sodium transport.

研究了白细胞钠转运，以此作为从经盐水输注扩容的正常受试者尿液中分离出的小分子重量利钠物质的一种可能检测方法。2. 该组分（组分四或FIV）在其他几种检测中对钠转运有抑制作用，也被发现能抑制白细胞钠转运。3. 从经历盐皮质激素“脱逸”性利钠的五名正常受试者尿液中分离出的FIV，也被发现对白细胞钠转运有抑制作用。4. 在盐皮质激素脱逸期间从同一受试者血液中分离出的白细胞显示钠转运减少。