Amenta F, Cavallotti C, Tassone F
G Ital Cardiol. 1977 Aug;7(8):756-9.
The relations between adrenergic nerve fibers and related receptors in the wall of the coronary arteries have been studied in man. On sections of these vessels morphological observations (H.E.) were carried out: histochemical staining of adrenergic mediators (Eranko reaction for norepinephrine, and Hillarp reaction for cathecolamines), and of beta-receptors by means of a beta-blocking fluorescent drug (pindolol-Visken LB 46). Our observations provide evidence of the presence of beta-receptors in the wall of the coronary arteries, but they are particularly concentrated in the periadventitial connective tissue, in the adventitia and in the intima-media transitional zone. Beta-adrenergic receptors are above all present in the most richly innervated part of the vascular wall, and are therefore in close rapport with adrenergic nerve fibers.
在人体中研究了冠状动脉壁内肾上腺素能神经纤维与相关受体之间的关系。对这些血管的切片进行了形态学观察（苏木精-伊红染色）：对肾上腺素能介质进行组织化学染色（用埃兰科反应检测去甲肾上腺素，用希拉尔普反应检测儿茶酚胺），并用一种β-阻断荧光药物（吲哚洛尔-维斯肯LB 46）对β受体进行染色。我们的观察结果证明冠状动脉壁内存在β受体，但它们特别集中在外膜周围结缔组织、外膜和内膜-中膜过渡区。β-肾上腺素能受体首先存在于血管壁神经支配最丰富的部位，因此与肾上腺素能神经纤维密切相关。
