Pizzi A, Taiuti R, Calandi C, Adami-Lami Conti C, Ghezzi M, Fratiglioni L, Marconi G
Riv Patol Nerv Ment. 1981 Mar-Apr;102(2):49-55.
An investigation was carried out to establish the incidence of X-linked progressive muscular dystrophies in Tuscany from 1966 to 1974. 52 cases were identified, the incidence being 23,95 X 10(-5) with reference to live-born males. The frequency of new mutations calculated according to Haldane's method was 7,97 X 10(-6). These data practically correspond to those reported by other AA. in Italy and abroad. There was also a remarkable variability in the incidence among individual districts with values ranging from 7,60 X 10(-5) to 41,91 X 10(-5). It was noticed that the number of new cases tended to decrease in the last few years.
一项调查旨在确定1966年至1974年托斯卡纳地区X连锁进行性肌营养不良症的发病率。共识别出52例病例，以活产男性为参照，发病率为23.95×10⁻⁵。根据霍尔丹方法计算的新突变频率为7.97×10⁻⁶。这些数据实际上与意大利和国外其他作者报告的数据相符。各地区发病率也存在显著差异，范围从7.60×10⁻⁵到41.91×10⁻⁵。人们注意到，新病例数在过去几年中呈下降趋势。
