Kaminskiĭ Iu G, Kosenko E A
Ukr Biokhim Zh (1978). 1982 May-Jun;54(3):289-92.
Diurnal variations of glycolytic intermediates and Pi concentrations are studied in the laboratory rat liver. It is shown that tissue concentrations of glucose, glucose-6-phosphate and Pi vary synchronously during the day exhibiting maxima in light period and minima at night. Circadian fructose 1,6-diphosphate rhythm is similar to the rhythms of the metabolites mentioned above. Diurnal variations of the phosphoenolpyruvate and pyruvate content in the tissue are shifted up to 3-6 h. The data indicate that circadian regulation of hepatic carbohydrate energy metabolism did not take place at control points of gluconeogenesis only.
在实验室大鼠肝脏中研究了糖酵解中间产物和无机磷酸盐（Pi）浓度的昼夜变化。结果表明，葡萄糖、6-磷酸葡萄糖和Pi的组织浓度在白天同步变化，在光照期达到最大值，在夜间达到最小值。昼夜节律性的1,6-二磷酸果糖节律与上述代谢物的节律相似。组织中磷酸烯醇丙酮酸和丙酮酸含量的昼夜变化提前了3 - 6小时。数据表明，肝脏碳水化合物能量代谢的昼夜调节并非仅发生在糖异生的控制点。
