Halberg E, Halberg F, Haus E, Cornélissen G, Wallach L A, Smolensky M, Garcia-Sainz M, Simpson H W, Shons A R
Chronobiologia. 1978 Jul-Sep;5(3):241-50.
A prophylactic bilateral subcutaneous mastectomy, following a preoperative mammogram revealed clustered small calcifications in the left breast. In order to investigate the merits of thermorphythmometry, the patient self-measured surface temperature of each breast, above and below the nipple, while awake. In the case here presented, bilateral subcutaneous mastectomy followed by extensive histologic scrutiny of both breasts revealed no indication of malignancy. Bilateral fibrocystic disease with calcification and lobular hyperplasia was found. As compared to the contralateral sites, the atypical epithelial proliferation was more abundant in the mammographically and thermorhythmometrically 'abnormal' area of the left breast.
在术前乳房X光检查发现左乳房有簇状小钙化灶后,患者接受了预防性双侧皮下乳房切除术。为了研究热节律测量法的优点,患者在清醒状态下自行测量了每个乳房乳头上下的表面温度。在本病例中,双侧皮下乳房切除术后对双侧乳房进行了广泛的组织学检查,未发现恶性肿瘤迹象。发现双侧乳腺纤维囊性疾病伴钙化和小叶增生。与对侧部位相比,左乳房在乳房X光检查和热节律测量“异常”区域的非典型上皮增生更为明显。