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特发性血小板减少性紫癜中铟 - 111标记血小板的动力学研究(作者译)

[Kinetic study of indium-111 labelled platelets in idiopathic thrombocytopenic purpura (author's transl)].

作者信息

Reiffers J, Vuillemin L, Broustet A, Ducassou D

出版信息

Nouv Presse Med. 1982 Jul 3;11(31):2335-8.

PMID:7202192
Abstract

Labelling platelets with 111 Indium-oxine has advantages over the conventional 51 Chromium method: labelling is more efficient and the radiations emitted almost exclusively consist of gamma-rays. Owing to these advantages, autologous platelets can be used for kinetic studies in patients with idiopathic thrombocytopenic purpura, even when thrombocytopenia is severe. 111 Indium labelling also provides accurate information on the sites of platelet destruction, which may help to predict the patient's response to splenectomy.

摘要

用铟-111 氧喹啉标记血小板比传统的铬-51 方法具有优势:标记效率更高,发射的辐射几乎完全由γ射线组成。由于这些优势,即使在血小板减少症严重的情况下,自体血小板也可用于特发性血小板减少性紫癜患者的动力学研究。铟-111 标记还能提供关于血小板破坏部位的准确信息,这可能有助于预测患者对脾切除术的反应。

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