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[使用氯前列醇(前列腺素F2α类似物)控制绵羊的性周期功能]

[Control of sex cycle functions in sheep using cloprostenol, an analog of prostaglandin F2a].

作者信息

Bankov N, Kunchev L, Stanchev F, Petrov P S, Pisheva M

出版信息

Vet Med Nauki. 1982;19(2):63-70.

PMID:7202283
Abstract

Studied was the synchronizing effect of the prostaglandin F2a analague - estrumate (ICI, England). with the Tsigai sheep. The investigations included observations on the clinical characteristics of the estrus, determination of the hormonal profile in naturally manifested estrus and in estrus induced with prostaglandin, and the conception rate with the first two successive estrus cycles along with the total conception. Estrumate was used twice ar a 9-day interval in a single dose of 125 mg, with a following programmed artificial insemination at the 48 h and the 72d hour after the second treatment. The conception rate with the first estrus of the ewes of the control and the test group was comparatively low - 41.3 and 30.4 per cent, and with the two successive cycles - 68.5 and 76.8 per cent, respectively. The total conception of the test group was 96.4 per cent as against 87.5 per cent of the control group. The studies on the content and dynamics of the basic hormones taking part in the endocrine regulation of the cycle functions in sheep with naturally manifested estrus and those with prostaglandine-unduced estrus did not show reliable differences in the hormonal profile. It was found that estrumate could successfully be used to synchronized the estrus cycle with the Tsigai sheep - a breed with pronounced conservatism' in the manifestation of cyclic functions.

摘要

研究了前列腺素F2α类似物——氯前列醇(ICI,英国)对茨盖羊的同期发情效果。研究包括观察发情的临床特征,测定自然发情和用前列腺素诱导发情时的激素水平,以及前两个连续发情周期的受胎率和总受胎率。氯前列醇以125毫克的单剂量,每隔9天使用两次,在第二次处理后的48小时和72小时进行程序化人工授精。对照组和试验组母羊第一个发情期的受胎率相对较低,分别为41.3%和30.4%,两个连续周期的受胎率分别为68.5%和76.8%。试验组的总受胎率为96.4%,而对照组为87.5%。对自然发情和前列腺素诱导发情的绵羊参与周期功能内分泌调节的基本激素含量和动态的研究表明,激素水平没有可靠差异。结果发现,氯前列醇可以成功地用于使茨盖羊的发情周期同期化,茨盖羊在周期功能表现上具有明显的保守性。

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