Hess H, Müller-Fassbender H, Ingrisch H, Mietaschk A
Dtsch Med Wochenschr. 1978 Dec 15;103(50):1994-7. doi: 10.1055/s-0028-1129383.
In a double-blind study, prevention of re-thrombosis was tested on 101 patients in whom stenosis or segmental occlusion of a large artery of the lower limbs had been successfully removed by the intraluminal catheter method. The combination of 75 mg dipyridamol and 330 mg acetylsalicylic acid, three times daily by mouth, proved to be slightly more effective than acetylsalicylic acid alone at the same dosage. In the group with the combined treatment 84% of the arteries remained open, compared with 70% on acetylsalicylic acid alone.
在一项双盲研究中，对101例下肢大动脉狭窄或节段性闭塞已通过腔内导管法成功解除的患者进行了再血栓形成预防测试。每日口服三次、每次75毫克双嘧达莫与330毫克阿司匹林的联合用药，在相同剂量下，被证明比单独使用阿司匹林稍有效。联合治疗组中84%的动脉保持通畅，而单独使用阿司匹林组这一比例为70%。
