[1-烯丙基-3,5-二乙基-6-氯尿嘧啶的第三种含硫代谢物的鉴定及SCH3-代谢物的形成机制（作者译）]
[Identification of a third S-containing metabolite of 1-allyl-3,5-diethyl-6-chlorouracil and mechanism of formation of SCH3-metabolites (author's transl)].
作者信息
Kaul R, Kiefer G, Hempel B
出版信息
Arzneimittelforschung. 1982;32(6):610-2.
PMID:7202365
Abstract
A new S-containing metabolite of 1-allyl-3,5-diethyl-6-chlorouracil is reported. By comparison with a synthetic product, this metabolite could be identified as 6,8-diethyl-2-hydroxymethyl-tetrahydrothiazolo-[3,2-c]pyrimidine-5,7 (4H,6H)-dione. The mechanism of the formation of S-containing metabolites is discussed.
摘要
报道了1-烯丙基-3,5-二乙基-6-氯尿嘧啶的一种新的含硫代谢物。通过与合成产物比较，该代谢物可鉴定为6,8-二乙基-2-羟甲基-四氢噻唑并-[3,2-c]嘧啶-5,7(4H,6H)-二酮。讨论了含硫代谢物的形成机制。
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