Fujishima T
Jikken Dobutsu. 1980 Oct;29(4):383-90.
Avoidance discrimination (right-left) and discriminated avoidance performances of 15 inbred strains of mice were measured on 50 learning trials in each of two daily sessions with a specially designed automated Y-type maze apparatus. Each trial consisted of light and buzzer for five seconds as conditioned stimuli and electric shock for five seconds as an unconditioned stimulus. Intertrial intervals were 30 seconds. The subjects were ten animals of 60-75 days of age for each sex. Highly significant differences among the strains for all the learning performances and negative correlations between the avoidance and discriminating performances of the strains were observed. This suggests that different strains should be chosen for avoidance and for discrimination, when used in behavioral experiments. Among the strains RF/Ms, SWM/Ms and SWR/Ms were superior in avoidance, while C3H/HeMs, DBA/2 and DBAf/Lw were superior in discrimination. C3h/HeMs and C57BL/6HeMs had relatively high abilities for both learning tasks. D103/Ms had the lowest learning ability in avoidance, while SWM/Ms and SWR/Ms had the lowest in discrimination.
使用专门设计的自动化Y型迷宫装置，在每天两个时段的每个时段进行50次学习试验，测量了15个近交系小鼠的回避辨别（左右）能力和辨别回避表现。每次试验包括5秒的灯光和蜂鸣声作为条件刺激，以及5秒的电击作为非条件刺激。试验间隔为30秒。实验对象为每种性别10只60 - 75日龄的动物。观察到各品系在所有学习表现上存在极显著差异，且品系的回避表现和辨别表现之间存在负相关。这表明在行为实验中，用于回避和辨别的品系应有所不同。在这些品系中，RF/Ms、SWM/Ms和SWR/Ms在回避方面表现出色，而C3H/HeMs、DBA/2和DBAf/Lw在辨别方面表现出色。C3h/HeMs和C57BL/6HeMs在两项学习任务中都具有相对较高的能力。D103/Ms在回避方面的学习能力最低，而SWM/Ms和SWR/Ms在辨别方面的学习能力最低。
