[Acrobullous photodermatitis caused by PUVA: measurement of dermo-epidermal adhesion].

In 65 patients suffering from psoriasis treated with photochemotherapy and 32 healthy controls the dermo-epidermal junction was measured by experimental blistering. A significantly shortened blistering time was shown in PUVA-patients. The reasons in discussion are the increase of activated melanocytes (clear cells) in the basal membrane region and changes in the connective tissue by long term PUVA-therapy.