Nittner H, Engelhart G, Hardmeier T, Ammann J
Helv Chir Acta. 1980 Dec;47(5):561-4.
Histological investigation leads to significantly more reliable evaluation of the B-2 stump than do clinical or endoscopic examinations. This is the result of our study, in which follow-up examinations in 58 patients were undertaken 25 to 30 years after B-2 resection for benign ulcer. Of these 58 patients 23 were examined endoscopically and histologically (22 patients). The histological results of interest are: early cancer, dysplasia and intestinal metaplasia. - Carcinoma of the gastric stump occurs only occasionally earlier than 15 years after resection. In order to detect more early cancers, we therefore suggest that a routine endoscopy and histological evaluation of the gastric mucosa should be undertaken 15 years after gastric resection for benign ulcer. Further follow-ups depend on the result of this "staging" of the gastric mucosa.
组织学检查对B-2残端的评估比临床或内镜检查更可靠得多。这是我们研究的结果,在该研究中,对58例因良性溃疡行B-2切除术后25至30年的患者进行了随访检查。这58例患者中,23例接受了内镜和组织学检查(22例患者)。感兴趣的组织学结果包括:早期癌症、发育异常和肠化生。——胃残端癌很少在切除术后15年之前出现。因此,为了发现更多早期癌症,我们建议在因良性溃疡行胃切除术后15年进行常规内镜检查和胃黏膜组织学评估。进一步的随访取决于胃黏膜这种“分期”检查的结果。