Bader G, Rohde E, Unger M, Koepcke E
Exp Pathol (Jena). 1978;16(1-6):121-5.
In 138 tokolytically treated cases of imminent abortion or premature birth the secundines were examined histologically and compared with 390 cases of pathological gravidities or births without tokolysis therapy. The frequency of occurrence of morphologically manifested circulatory disturbances following tokolysis therapy was equal to that in the untreated cases, the rate of ascendent infections was only slightly increased. In tokolytically treated placentas with the histological pattern of "dissociated disturbed maturation" and "Maturitias retarda" are prevailing. Thus in most cases sufficient supply of the fetus is possible and the critical phase of uteroplacental insufficiency with the danger of abortion or premature birth may be overcome. There were no hints at direct influences of tokolysis on placental morphology.
在138例接受宫缩抑制治疗的先兆流产或早产病例中,对胎盘胎膜进行了组织学检查,并与390例未接受宫缩抑制治疗的病理妊娠或分娩病例进行了比较。宫缩抑制治疗后形态学上表现出的循环障碍的发生率与未治疗病例相同,上行感染率仅略有增加。在接受宫缩抑制治疗的胎盘中,以“解离性成熟障碍”和“成熟延迟”的组织学模式为主。因此,在大多数情况下,胎儿的充足供应是可能的,子宫胎盘功能不全的关键阶段以及流产或早产的危险可能会被克服。没有迹象表明宫缩抑制对胎盘形态有直接影响。