Blackburn A M, Bryant M G, Adrian T E, Bloom S R
J Clin Endocrinol Metab. 1981 Apr;52(4):820-2. doi: 10.1210/jcem-52-4-820.
Tumour tissue may secrete substances which are not normally secreted by the original tissue. We have found that 6 out of 21 pancreatic tumours producing vasoactive intestinal peptide also produce neurotensin-like peptides. These are sometimes secreted and very high plasma levels of neurotensin-like immunoreactivity may be found in the circulation.
肿瘤组织可能分泌一些正常情况下原始组织不会分泌的物质。我们发现,在21例产生血管活性肠肽的胰腺肿瘤中,有6例还产生神经降压素样肽。这些肽有时会被分泌出来,在循环中可能会发现血浆中神经降压素样免疫反应性水平非常高。