Levy M, Ehrenfeld M, Levo Y, Fischel R, Zlotnick A, Eliakim M
J Rheumatol. 1980 Nov-Dec;7(6):886-90.
Increased levels of circulating immune complexes (CIC) were demonstrated by the Clq binding assay in 22 (27%) out of 81 patients with recurrent polyserositis. The prevalence of increased CIC was significantly higher in Jewish patients of North African origin (42%) than in subjects of other ethnic groups (6%). North African patients also manifested an increased familial incidence, earlier onset of symptoms and a higher frequency of arthritis. There was no correlation between increased CIC levels and disease activity. These findings suggest that the immune response of North African patients differs from that of subjects of other ethnic groups and that this difference is possibly genetically determined.
在81例复发性多浆膜炎患者中，通过Clq结合试验证实，22例（27%）患者循环免疫复合物（CIC）水平升高。北非裔犹太患者中CIC升高的患病率（42%）显著高于其他种族人群（6%）。北非患者还表现出家族发病率增加、症状出现较早以及关节炎发生率较高。CIC水平升高与疾病活动度之间无相关性。这些发现表明，北非患者的免疫反应与其他种族人群不同，这种差异可能由基因决定。
