Noskov V B, Grigor'ev A I
Farmakol Toksikol. 1978 Nov-Dec;41(6):704-8.
Dexamethazone at a single dose of 2 mg caused in the next 24 hours retention in the organism of a healthy man of a liquid and salts against the background of an abrupt fall of excretion by the kidneys of 17-oxycorticosteroids. Most distinctly this effect manifested itself after an aqueous test (20 ml/kg). A functional test with dexamethazone may be used clinically in assessing the condition of the hormonal link of the water-electrolyte metabolism regulation and renal function.
单次服用2毫克地塞米松会在接下来的24小时内,使一名健康男性机体中的液体和盐分潴留,此时肾脏排泄17 - 氧皮质类固醇的量会急剧下降。在水负荷试验(20毫升/千克)后,这种效应表现得最为明显。地塞米松功能试验可在临床上用于评估水 - 电解质代谢调节的激素环节状况及肾功能。