• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Norethisterone-4 beta,5-oxide and laevonorgestrel-4 beta,5-oxide: formation in rat liver microsomal incubations and interference with microsomal epoxide hydrolase and cytoplasmic glutathione S-transferase.

作者信息

Peter H, Jung R, Bolt H M, Oesch F

出版信息

J Steroid Biochem. 1981 Jan;14(1):83-90. doi: 10.1016/0022-4731(81)90196-5.

DOI:10.1016/0022-4731(81)90196-5
PMID:7206700
Abstract
摘要

相似文献

1
Norethisterone-4 beta,5-oxide and laevonorgestrel-4 beta,5-oxide: formation in rat liver microsomal incubations and interference with microsomal epoxide hydrolase and cytoplasmic glutathione S-transferase.
J Steroid Biochem. 1981 Jan;14(1):83-90. doi: 10.1016/0022-4731(81)90196-5.
2
Inhibition of epoxide hydrolases and glutathione S-transferases by 2-, 3-, and 4-substituted derivatives of 4'-phenylchalcone and its oxide.4'-苯基查尔酮及其氧化物的2-、3-和4-取代衍生物对环氧水解酶和谷胱甘肽S-转移酶的抑制作用
Arch Biochem Biophys. 1987 Apr;254(1):203-13. doi: 10.1016/0003-9861(87)90096-8.
3
Chemical reactivity and metabolism of norethindrone-4 beta,5 beta-epoxide by rat liver microsomes in vitro.炔诺酮-4β,5β-环氧化物在大鼠肝脏微粒体中的体外化学反应性与代谢
Chem Biol Interact. 1980 Jan;29(1):103-15. doi: 10.1016/0009-2797(80)90090-3.
4
Effect of selected induction of microsomal and nuclear aryl hydrocarbon monooxygenase and epoxide hydrolase as well as cytoplasmic glutathione S-epoxide transferase on the covalent binding of the carcinogen benzo(a)pyrene to rat liver DNA in vivo.微粒体和细胞核芳烃单加氧酶、环氧化物水解酶以及细胞质谷胱甘肽S-环氧化物转移酶的特定诱导对致癌物苯并(a)芘在体内与大鼠肝脏DNA共价结合的影响。
J Cancer Res Clin Oncol. 1980;98(2):139-52. doi: 10.1007/BF00405958.
5
Gadolinium chloride inhibition of rat hepatic microsomal epoxide hydrolase and glutathione S-transferase gene expression.氯化钆对大鼠肝脏微粒体环氧化物水解酶和谷胱甘肽S-转移酶基因表达的抑制作用。
Drug Metab Dispos. 1997 Dec;25(12):1416-23.
6
Cyclopropyl oxiranes: reversible inhibitors of cytosolic and microsomal epoxide hydrolases.
Arch Biochem Biophys. 1985 Mar;237(2):361-72. doi: 10.1016/0003-9861(85)90288-7.
7
Metabolism of tridiphane (2-(3,5-dichlorophenyl)-2(2,2,2-trichloroethyl)oxirane) by hepatic epoxide hydrolases and glutathione S-transferases in mouse.小鼠肝脏环氧化物水解酶和谷胱甘肽S-转移酶对三环锡(2-(3,5-二氯苯基)-2(2,2,2-三氯乙基)环氧乙烷)的代谢作用
Toxicol Appl Pharmacol. 1987 Dec;91(3):439-49. doi: 10.1016/0041-008x(87)90065-2.
8
Differential induction of cytosolic epoxide hydrolase, microsomal epoxide hydrolase, and glutathione S-transferase activities.胞质环氧化物水解酶、微粒体环氧化物水解酶和谷胱甘肽S-转移酶活性的差异诱导。
Toxicol Appl Pharmacol. 1983 Nov;71(2):254-65. doi: 10.1016/0041-008x(83)90342-3.
9
An in vitro study of the microsomal metabolism and cellular toxicity of phenytoin, sorbinil and mianserin.苯妥英、索比尼尔和米安色林的微粒体代谢及细胞毒性的体外研究。
Br J Clin Pharmacol. 1988 Nov;26(5):577-88. doi: 10.1111/j.1365-2125.1988.tb05298.x.
10
Benzene metabolism by reconstituted cytochromes P450 2B1 and 2E1 and its modulation by cytochrome b5, microsomal epoxide hydrolase, and glutathione transferases: evidence for an important role of microsomal epoxide hydrolase in the formation of hydroquinone.重组细胞色素P450 2B1和2E1介导的苯代谢及其受细胞色素b5、微粒体环氧化物水解酶和谷胱甘肽转移酶的调节:微粒体环氧化物水解酶在对苯二酚形成中起重要作用的证据
Toxicol Appl Pharmacol. 1993 Oct;122(2):172-81. doi: 10.1006/taap.1993.1185.

引用本文的文献

1
Investigations on the in vitro metabolism of five synthetic 19-norprogestins using hepatocyte suspensions isolated from five laboratory animal species.
Eur J Drug Metab Pharmacokinet. 1991 Apr-Jun;16(2):93-102. doi: 10.1007/BF03189944.