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无症状性及扩张性腹主动脉瘤患者的长期随访(作者译)

[Long-term follow-up of patients asymptomatic and expanding abdominal aortic aneurysms (author's transl)].

作者信息

Ruckert R F, Meier W E, Senning A

出版信息

Langenbecks Arch Chir. 1980;353(3):193-9. doi: 10.1007/BF01261963.

Abstract

In a retrospective study, 268 patients with all three types of abdominal aortic aneurysms (AAA) were analyzed. They had been seen at the Surgical Clinic A of the University Hospital in Zurich, Switzerland, from 1961 through 1977. The follow-up included 97% of the surgical and all nonsurgical cases. This report is based on the analysis of the 167 surgically and 16 nonsurgically treated patients with asymptomatic (I) or expanding (II) AAA. Of the 16 patients not operated on, 15 died after a mean time of 13 months after examination, 57% due to rupture and 29% because of coronary heart disease. In the operative group, the 30-day perioperative mortality was 7% for the asymptomatic AAA and 14% for the expanding. Late mortality reached 25% for type I and 37% for type II after a mean survival time of 50 months. Of all surgically treated patients, 58% could be examined 1-14 (mean 4) years after aneurysmectomy. The cumulative survival rate for the 5th year reached 73% in the surgical asymptomatic group and 48% in the expanding or 62% for both; the nonsurgical group had a survival rate of only 6%. The results of the long-term follow-up are described in detail as well as the various factors related to arteriosclerosis or to surgery with statistically significant influence on prognosis. Comparison of the late results of all three types of AAA and confrontation with the spontaneous course of the disease emphasize the importance of early indication for operation.

摘要

在一项回顾性研究中,对268例患有所有三种类型腹主动脉瘤(AAA)的患者进行了分析。他们于1961年至1977年期间在瑞士苏黎世大学医院的外科诊所A接受诊治。随访涵盖了97%的手术病例和所有非手术病例。本报告基于对167例接受手术治疗以及16例接受非手术治疗的无症状(I型)或扩张性(II型)腹主动脉瘤患者的分析。在这16例未接受手术的患者中,15例在检查后平均13个月死亡,57%死于破裂,29%死于冠心病。在手术组中,无症状腹主动脉瘤患者的围手术期30天死亡率为7%,扩张性腹主动脉瘤患者为14%。I型患者平均生存50个月后的晚期死亡率为25%,II型为37%。在所有接受手术治疗的患者中,58%在动脉瘤切除术后1 - 14年(平均4年)接受了检查。手术无症状组第5年的累积生存率达到73%,扩张性腹主动脉瘤组为48%,两者合并为62%;非手术组的生存率仅为6%。详细描述了长期随访结果以及与动脉硬化或手术相关的各种对预后有统计学显著影响的因素。对所有三种类型腹主动脉瘤的晚期结果进行比较,并与疾病的自然病程相对照,强调了早期手术指征的重要性。

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