• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

仓鼠成纤维细胞新合成的细胞质核糖体中蛋白质S6的磷酸化作用。

The phosphorylation of protein S6 in the newly-synthesized cytoplasmic ribosomes of hamster fibroblasts.

作者信息

Kennedy I M, Leader D P

出版信息

Mol Biol Rep. 1980 Dec 31;6(4):199-202. doi: 10.1007/BF00777524.

DOI:10.1007/BF00777524
PMID:7207470
Abstract

Ribosomes were isolated from baby hamster kidney fibroblasts, either 20 min or 2 days after labelling with radioactive amino acids, and their proteins subjected to two-dimensional polyacrylamide gel electrophoresis. No significant differences were observed between the amounts of radioactivity associated with the position of the phosphorylated derivatives of protein S6. This suggests that the phosphorylation is unlikely to be important in ribosomal biogenesis or extranuclear transport.

摘要

从用放射性氨基酸标记后的幼仓鼠肾成纤维细胞中分离核糖体，标记时间分别为20分钟或2天，然后将其蛋白质进行二维聚丙烯酰胺凝胶电泳。在与蛋白质S6磷酸化衍生物位置相关的放射性量之间未观察到显著差异。这表明磷酸化在核糖体生物合成或核外运输中不太可能起重要作用。

相似文献

1
The phosphorylation of protein S6 in the newly-synthesized cytoplasmic ribosomes of hamster fibroblasts.仓鼠成纤维细胞新合成的细胞质核糖体中蛋白质S6的磷酸化作用。
Mol Biol Rep. 1980 Dec 31;6(4):199-202. doi: 10.1007/BF00777524.
2
The phosphorylation of ribosomal protein S6 in hamster fibroblasts infected with pseudorabies virus inactivated by ultraviolet radiation.感染经紫外线灭活的伪狂犬病病毒的仓鼠成纤维细胞中核糖体蛋白S6的磷酸化作用
J Gen Virol. 1984 Sep;65 ( Pt 9):1621-4. doi: 10.1099/0022-1317-65-9-1621.
3
The phosphorylation of ribosomal protein S6 in baby hamster kidney fibroblasts.幼仓鼠肾成纤维细胞中核糖体蛋白S6的磷酸化作用
Biochem Biophys Res Commun. 1976 Aug 23;71(4):966-74. doi: 10.1016/0006-291x(76)90749-x.
4
Increased phosphorylation of ribosomal protein S6 in hamster fibroblasts transformed by polyoma virus and simian virus 40.在多瘤病毒和猿猴病毒40转化的仓鼠成纤维细胞中核糖体蛋白S6磷酸化增加。
Biochem J. 1981 Jul 15;198(1):235-7. doi: 10.1042/bj1980235.
5
Induction, partial purification and characterization of a hamster fibroblast protein kinase activity that phosphorylates ribosomal protein S6.磷酸化核糖体蛋白S6的仓鼠成纤维细胞蛋白激酶活性的诱导、部分纯化及特性鉴定
Eur J Biochem. 1987 Apr 1;164(1):83-8. doi: 10.1111/j.1432-1033.1987.tb10996.x.
6
Separation of multiple phosphorylated forms of 40 S ribosomal protein S6 by two-dimensional polyacrylamide gel electrophoresis.
Methods Enzymol. 1987;146:362-9. doi: 10.1016/s0076-6879(87)46037-0.
7
The phosphorylation of eukaryotic ribosomal protein S6 by protein kinase C.蛋白激酶C对真核生物核糖体蛋白S6的磷酸化作用。
Eur J Biochem. 1985 May 2;148(3):579-86. doi: 10.1111/j.1432-1033.1985.tb08879.x.
8
Heat shock causes diverse changes in the phosphorylation of the ribosomal proteins of mammalian cells.热休克会导致哺乳动物细胞核糖体蛋白磷酸化发生多种变化。
FEBS Lett. 1984 Apr 24;169(2):267-73. doi: 10.1016/0014-5793(84)80331-2.
9
The activity of protein kinases from hamster fibroblasts towards a synthetic peptide based on a carboxy-terminal portion of ribosomal protein S6.仓鼠成纤维细胞中蛋白激酶对基于核糖体蛋白S6羧基末端部分的合成肽的活性。
Biochim Biophys Acta. 1990 Sep 1;1054(2):225-30. doi: 10.1016/0167-4889(90)90245-9.
10
Protease-activated kinase II as the mediator of epidermal growth factor-stimulated phosphorylation of ribosomal protein S6.蛋白酶激活激酶II作为表皮生长因子刺激核糖体蛋白S6磷酸化的介质。
FEBS Lett. 1985 Apr 22;183(2):215-8. doi: 10.1016/0014-5793(85)80779-1.

本文引用的文献

1
Phosphorylation of ribosomal proteins in rabbit reticulocytes. Characterization and regulatory aspects.兔网织红细胞中核糖体蛋白的磷酸化。特性及调控方面。
Biochemistry. 1970 Oct 13;9(21):4160-75. doi: 10.1021/bi00823a019.
2
Enzymatic phosphorylation of eukaryotic ribosomal proteins and factors of protein biosynthesis.
Acta Biol Med Ger. 1974;33(5-6):667-76.
3
The stimulation of the phosphorylation of ribosomal protein S6 by cycloheximide and puromycin.放线菌酮和嘌呤霉素对核糖体蛋白S6磷酸化的刺激作用。
Biochem Biophys Res Commun. 1974 Oct 23;60(4):1482-90. doi: 10.1016/0006-291x(74)90365-9.
4
The phosphorylation of liver ribosomal proteins in vivo. Evidence that only a single small subunit protein (S6) is phosphorylated.肝脏核糖体蛋白在体内的磷酸化。证据表明只有单个小亚基蛋白（S6）被磷酸化。
J Biol Chem. 1974 Nov 10;249(21):6917-25.
5
Effect of cyclic adenosine 3':5'-monophosphate on ribosomal protein phosphorylation in reticulocytes.3':5'-环磷酸腺苷对网织红细胞核糖体蛋白磷酸化的影响。
J Biol Chem. 1974 Jan 10;249(1):275-8.
6
The phosphorylation of ascites cell ribosomes in vivo: identification of a phosphorylated protein of the small ribosomal subunit by two-dimensional gel electrophoresis.体内腹水细胞核糖体的磷酸化：通过二维凝胶电泳鉴定小核糖体亚基的一种磷酸化蛋白。
FEBS Lett. 1975 Apr 1;52(2):284-7. doi: 10.1016/0014-5793(75)80826-x.
7
The phosphorylation of ribosomal protein S6 in baby hamster kidney fibroblasts.幼仓鼠肾成纤维细胞中核糖体蛋白S6的磷酸化作用
Biochem Biophys Res Commun. 1976 Aug 23;71(4):966-74. doi: 10.1016/0006-291x(76)90749-x.
8
The phosphorylation of the ribosomal proteins of Krebs II ascites cells.克氏腹水癌细胞核糖体蛋白的磷酸化作用
Biochim Biophys Acta. 1977 Jan 20;474(2):293-307. doi: 10.1016/0005-2787(77)90203-9.
9
The ribosomal proteins of Saccharomyces cerevisiae. Phosphorylated and exchangeable proteins.酿酒酵母的核糖体蛋白。磷酸化和可交换蛋白。
J Biol Chem. 1976 Mar 25;251(6):1799-807.
10
The phosphorylation of ribosomal protein S6 on the monoribosomes and polyribosomes of baby hamster kidney fibroblasts.幼仓鼠肾成纤维细胞单核糖体和多核糖体上核糖体蛋白S6的磷酸化作用
FEBS Lett. 1978 Jun 15;90(2):270-4. doi: 10.1016/0014-5793(78)80383-4.