Lindvall S, Rydén L, Smedgärd P, Swedberg B
Scand J Haematol. 1980 Oct;25(4):331-8. doi: 10.1111/j.1600-0609.1981.tb01411.x.
At the onset of disturbances of cardiac rhythm after a 7th injection of iron sorbitol to a patient with severe malabsorption syndrome an extremely low level of alpha-tocopherol in serum--0.04 mg per 100 ml serum--was observed. The clinical manifestations are interpreted as a possible consequence of the depletion of the vitamin, a natural scavenger of free radicals. The possible importance of alpha-tocopherol in preventing the toxic effect of iron on the apparently very sensitive myocardium after parenteral iron to patients with severe malabsorption syndrome is discussed.
在对一名患有严重吸收不良综合征的患者第七次注射山梨醇铁后出现心律失常时，观察到血清中α-生育酚水平极低——每100毫升血清中仅0.04毫克。临床表现被解释为这种维生素（自由基的天然清除剂）耗竭的可能后果。文中讨论了α-生育酚在预防严重吸收不良综合征患者经肠道外补铁后铁对明显非常敏感的心肌产生毒性作用方面的潜在重要性。
