Lund J O, Elmgreen J, Gammelgaard P A, Hansner E
Scand J Urol Nephrol. 1980;14(3):292-6. doi: 10.3109/00365598009179579.
Adrenal scintigraphy with 131I-19-iodo-cholesterol was performed in 13 hypertensive patients with biochemical disturbances suggesting an aldosterone-producing adenoma. The actual presence of an adenoma was subsequently confirmed in all cases. An asymmetrical tracer uptake (lateralization) was seen in 7 patients and in 6 of these the adenoma was located in the adrenal with the higher uptake. In one patient a large necrotic tumour was not visualized and a faint contralateral accumulation was wrongly taken to represent a tumour. In 6 patients the scintigram was non-lateralizing. In these highly selected patients a lateralizing scintigram had a high diagnostic specificity and at present adrenal scintigraphy should be the method of first choice in the preoperative side prediction. However, the sensitivity is low: a non-lateralizing scintigram does not exclude the presence of an aldosterone-producing adenoma.
对13例有生化紊乱提示醛固酮分泌性腺瘤的高血压患者进行了131I-19-碘胆固醇肾上腺闪烁显像。随后在所有病例中均证实腺瘤实际存在。7例患者可见不对称的示踪剂摄取（侧化），其中6例腺瘤位于摄取较高的肾上腺。1例患者有一个大的坏死肿瘤未显影，对侧的微弱积聚被错误地认为代表肿瘤。6例患者闪烁显像无侧化。在这些经过高度挑选的患者中，侧化闪烁显像具有很高的诊断特异性，目前肾上腺闪烁显像应作为术前定位预测的首选方法。然而，其敏感性较低：无侧化的闪烁显像不能排除醛固酮分泌性腺瘤的存在。
