Papachristou D N, Shiu M H
Surg Gynecol Obstet. 1981 Apr;152(4):483-7.
During the period of 1949 to 1971, 72 patients at this cancer center underwent en bloc multiple organ resection with curative intent for adenocarcinoma of the stomach that had invaded adjacent organs and structures. The over-all five year survival rate was 7 per cent and the operative mortality, 37.5 per cent. Patients with advanced stage tumors did poorly, although relief of symptoms and some prolongation of survival time were evident. Those patients with early staged tumors limited to the stomach and adjacent perigastric lymph nodes had a remarkable salvage rate of 31 per cent for a corresponding operative mortality of 25 per cent. Most of the postoperative complications and deaths occurred in the earlier period of the study and are preventable with present day surgical management; few deaths occurred during the last five years of the study. In the absence of detectable distant metastases, aggressive resection of these tumors is warranted in carefully selected patients with reasonable prospects of cure and palliation.
在1949年至1971年期间，该癌症中心有72例患者因侵犯相邻器官和结构的胃腺癌接受了旨在治愈的整块多器官切除术。总体五年生存率为7%，手术死亡率为37.5%。晚期肿瘤患者预后较差，尽管症状缓解和生存时间有所延长是明显的。那些肿瘤局限于胃和相邻胃周淋巴结的早期患者有显著的挽救率，为31%，相应的手术死亡率为25%。大多数术后并发症和死亡发生在研究的早期阶段，采用当今的外科治疗方法是可以预防的；在研究的最后五年中很少有死亡发生。在没有可检测到的远处转移的情况下，对于经过精心挑选、有合理治愈和缓解希望的患者，积极切除这些肿瘤是必要的。
