Nordenbo A M, Sørensen P S
Acta Neurol Scand. 1981 Apr;63(4):237-46. doi: 10.1111/j.1600-0404.1981.tb00777.x.
The incidence of neurosyphilis in the Greater Copenhagen region was found to be 0.30 per 100,000 inhabitants per year within a 5 year period. This figure is higher than incidence found in other studies from the last decades, but does not represent a statistically significant rise. Using hospital records from relevant departments 23 patients were described. General paresis and meningovascular cases were the most common manifestations. A tendency towards a changing clinical pattern of neurosyphilis was confirmed. Dementia and personality changes were the most frequently observed clinical symptoms. The classical signs of tabes dorsalis were seen in only very few patients. Stroke was a common manifestation. We recommend Standard Serological Tests for Syphilis to be carried out in patients under 60 years of age with cerebrovascular diseases, dementia and in patients where neurosyphilis could be even a remote diagnostic possibility.
在哥本哈根大区，5年期间神经梅毒的发病率为每年每10万居民0.30例。这一数字高于过去几十年其他研究中的发病率，但并不代表有统计学意义的上升。利用相关科室的医院记录描述了23例患者。全身性麻痹和脑膜血管性病例是最常见的表现。神经梅毒临床模式变化的趋势得到了证实。痴呆和人格改变是最常观察到的临床症状。仅在极少数患者中出现了脊髓痨的典型体征。中风是一种常见表现。我们建议对60岁以下患有脑血管疾病、痴呆的患者以及可能存在神经梅毒诊断可能性的患者进行梅毒标准血清学检测。
