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溃疡性斑块在短暂性脑缺血中的意义。

Significance of ulcerated plaque in transient cerebral ischemia.

作者信息

Bartynski W S, Darbouze P, Nemir P

出版信息

Am J Surg. 1981 Mar;141(3):353-7. doi: 10.1016/0002-9610(81)90195-1.

DOI:10.1016/0002-9610(81)90195-1
PMID:7212183
Abstract

The results of 210 endarterectomies in 174 patients are reviewed. The average age was 60.3 years for women and 62.1 years for men, with women comprising 53 percent of the population. Pathologic evaluation of tissue removed at time of surgery revealed macroscopic ulcerations in 50 percent of specimens and microscopic ulcerations in 33 percent, with 15 percent of specimens having both macroscopic and microscopic ulcerations. We were unable to identify a set of factors on the basis of symptoms or preoperative studies that would unequivocally indicate ulceration, but we believe that this study reinforces the concept that atheromatous embolization is probably a more frequent remedial cause of transient ischemic attacks than ischemia secondary to large vessel disease.

摘要

回顾了174例患者210次动脉内膜切除术的结果。女性的平均年龄为60.3岁,男性为62.1岁,女性占总人数的53%。手术时切除组织的病理评估显示,50%的标本有肉眼可见的溃疡,33%有显微镜下可见的溃疡,15%的标本同时有肉眼和显微镜下可见的溃疡。我们无法根据症状或术前研究确定一组能明确提示溃疡的因素,但我们认为这项研究强化了这样一个概念,即动脉粥样硬化栓塞可能是短暂性脑缺血发作比大血管疾病继发缺血更常见的补救原因。

相似文献

1
Significance of ulcerated plaque in transient cerebral ischemia.溃疡性斑块在短暂性脑缺血中的意义。
Am J Surg. 1981 Mar;141(3):353-7. doi: 10.1016/0002-9610(81)90195-1.
2
Ulcerated atheroma of the carotid artery. A cause of transient cerebral ischemia.颈动脉粥样硬化溃疡。短暂性脑缺血的一个病因。
Am J Surg. 1968 Aug;116(2):237-42. doi: 10.1016/0002-9610(68)90499-6.
3
Surgical management of extracranial vascular disease.颅外血管疾病的外科治疗
Cardiovasc Clin. 1971;3(1):203-31.
4
Ultramicroscopic ulcerations and thrombi of the carotid bifurcation.颈动脉分叉处的超微溃疡和血栓形成。
Arch Surg. 1977 Nov;112(11):1394-1402. doi: 10.1001/archsurg.1977.01370110128015.
5
Amaurosis fugax and transient ischemic attacks secondary to proximal carotid artery lesions.
Am Surg. 1983 Jan;49(1):18-20.
6
Atheromatous emboli in mural capillaries of carotid endarterectomy specimens.颈动脉内膜切除术标本壁内毛细血管中的动脉粥样硬化栓子。
Surg Neurol. 1984 Feb;21(2):141-7. doi: 10.1016/0090-3019(84)90332-x.
7
Significance of nonstenotic carotid bifurcation plaques.非狭窄性颈动脉分叉斑块的意义
Am Fam Physician. 1985 Oct;32(4):117-25.
8
Carotid endarterectomy for nonhemispheric transient ischemic attacks.
Arch Surg. 1975 Nov;110(11):1314-7. doi: 10.1001/archsurg.1975.01360170054007.
9
The carotid bifurcation plaque: pathologic findings associated with cerebral ischemia.颈动脉分叉处斑块:与脑缺血相关的病理 findings
Stroke. 1979 May-Jun;10(3):238-45. doi: 10.1161/01.str.10.3.238.
10
Cerebral complications of ulcerated atheromata at the carotid bifurcation.颈动脉分叉处溃疡性动脉粥样硬化的脑部并发症。
J Am Geriatr Soc. 1972 Jan;20(1):25-9. doi: 10.1111/j.1532-5415.1972.tb01197.x.

引用本文的文献

1
Extracranial arterial reconstruction for atheromatous stenotic disease.
Surg Today. 1994;24(10):859-69. doi: 10.1007/BF01651000.
2
The importance of hemorrhage in the relationship between gross morphologic characteristics and cerebral symptoms in 376 carotid artery plaques.376例颈动脉斑块的大体形态特征与脑部症状关系中出血的重要性。
Ann Surg. 1983 Feb;197(2):195-203. doi: 10.1097/00000658-198302000-00012.
3
Amaurosis fugax.一过性黑矇
Br Med J (Clin Res Ed). 1982 Oct 16;285(6348):1066-8. doi: 10.1136/bmj.285.6348.1066.
4
Perioperative stroke. Part I: General surgery, carotid artery disease, and carotid endarterectomy.围手术期卒中。第一部分:普通外科、颈动脉疾病和颈动脉内膜切除术。
Can J Anaesth. 1991 Apr;38(3):347-73. doi: 10.1007/BF03007628.