Clarke I M
Anaesthesia. 1981 Feb;36(2):210-2. doi: 10.1111/j.1365-2044.1981.tb08728.x.
One-hundred and twenty patients with chronic pain, who had all failed to obtain relief with traditional medical treatment, were given a standard psychotropic drug mixture consisting of amitriptyline 25 mg and perphenazine 2 mg. Of those who completed 2 months of treatment, 33.68% were pain free, while 8.3% had unacceptable side-effects. The best results were obtained in patients with postherpetic neuralgia and postoperative scar pain.
120名患有慢性疼痛且传统医学治疗均未能缓解疼痛的患者，接受了由25毫克阿米替林和2毫克奋乃静组成的标准精神药物混合治疗。在完成2个月治疗的患者中，33.68%的患者疼痛消失，而8.3%的患者出现了难以接受的副作用。疱疹后神经痛和术后瘢痕疼痛患者取得了最佳治疗效果。
