Magalhães M M, Magalhães M C
Anat Rec. 1980 Oct;198(2):209-18. doi: 10.1002/ar.1091980208.
Macrophages of the adrenal cortex were studied in normal and orchidectomized rats. In normal rats, few macrophages with numerous cytoplasmic granules were observed, mainly in the zona reticularis. Granules were limited by a single membrane and contained either a finely granular dense matrix or heterogeneous materials made up of electron-lucent parts, dark granular and membranous areas. An aminotriazole-resistant peroxidatic activity was confined to the dense granules. In orchidectomized rats, the number of macrophages was markedly increased, and the cells were concentrated at the border between the zonae fasciculata and reticularis and disseminated throughout the zona reticularis. Lysosomes were more numerous in each macrophage, and those of heterogeneous matrix were larger and their contents were more complex than in normal rats. These results show that orchidectomy stimulates the adrenal macrophage system.
对正常和去势大鼠的肾上腺皮质巨噬细胞进行了研究。在正常大鼠中，主要在网状带观察到少数具有大量细胞质颗粒的巨噬细胞。颗粒由单层膜包被，内含细颗粒状致密基质或由电子透明部分、深色颗粒和膜状区域组成的异质物质。抗氨基三唑的过氧化物酶活性局限于致密颗粒。在去势大鼠中，巨噬细胞数量明显增加，细胞集中在束状带和网状带之间的边界，并散布于整个网状带。每个巨噬细胞中的溶酶体数量更多，与正常大鼠相比，异质基质的溶酶体更大且内容物更复杂。这些结果表明，去势刺激肾上腺巨噬细胞系统。
