Young C D, Moore G W, Hutchins G M
Anat Rec. 1980 Oct;198(2):245-54. doi: 10.1002/ar.1091980211.
Connective tissue provides dynamic stability to the architecture and mechanical function of the lungs. This study examines the parenchymal connective tissue components of the alveolar ducts, their associated respiratory bronchioles and respective alveoli. Thick sections 100 mu and 200 mu, and serial sections at 8 mu of lungs of different ages were examined histologically after fixation in distention. The varying proportions and spatial architecture of the collagen and elastic fibers and the packing and spatial interrelationships of alveoli were studied using graphic serial reconstruction. Alveolar mouth typically have a polygonal configuration as they arise from the airways. Denser connective tissue passes through the polygonal array and forms a helix encircling the airway. Polygonal packing of alveolar mouths provides a mechanically stable ductular structure with conservation of materials. A helical modification of the polygonal arrangement permits reversible changes in linear and circumferential airway dimensions.
结缔组织为肺的结构和机械功能提供动态稳定性。本研究检查了肺泡管的实质结缔组织成分、其相关的呼吸性细支气管和各自的肺泡。对不同年龄的肺在扩张状态下固定后制作的100微米和200微米厚的切片以及8微米的连续切片进行组织学检查。使用图形连续重建研究了胶原纤维和弹性纤维的不同比例和空间结构以及肺泡的排列和空间相互关系。肺泡口从气道发出时通常呈多边形结构。较致密的结缔组织穿过多边形阵列并形成围绕气道的螺旋。肺泡口的多边形排列提供了一种机械稳定的导管结构并节省了材料。多边形排列的螺旋状改变允许气道的线性和圆周尺寸发生可逆变化。
