Oliete García F, Herrera Andújar P, Pérez Carmona N J, Balboa de Paz F
An Esp Pediatr. 1980 Nov;13(11):1017-22.
A case history of a two years seven months old boy with hyperinsulinism and marked psychomotor retardation is presented. In this patient, biochemical analysis revealed persistent hypoglycemia. Basal insulin levels (RIA) were consistently superior to 10 mU/ml. and were higher than would be expected from the child's glycemias. Angiographic study of the celiac trunk revealed diffuse pancreatic enlargement. Therapy was initiated with oral diazoxide normalizing and stabilizing the patient's glycemia. The importance of an early diagnosis of this condition and the necessary biochemical analyses involved are discussed as well as the use of diazoxide in the medical treatment of hypoglycemia.
本文介绍了一名两岁七个月大患有高胰岛素血症和明显精神运动发育迟缓男孩的病例史。该患者经生化分析显示持续性低血糖。基础胰岛素水平（放射免疫分析法）持续高于10 mU/ml，且高于根据患儿血糖水平所预期的数值。腹腔干血管造影研究显示胰腺弥漫性肿大。开始使用口服二氮嗪进行治疗，使患者血糖恢复正常并稳定。文中讨论了该病早期诊断的重要性以及所涉及的必要生化分析，还讨论了二氮嗪在低血糖药物治疗中的应用。
