Singh S P, Sisodia A K, Barthwal S P, Indrayan A, Bhushan S, Seth P
Indian J Physiol Pharmacol. 1978 Jul-Sep;22(3):270-8.
Daily urinary creatinine excretion and creatinine coefficient of eighty-four healthy medical students have been studied for three consecutive days. Daily creatinine excretion has been observed to be higher in the male subjects compared to the female counterparts. Creatinine excretion has been observed to be dependent on body weight of the subjects. The variability from subject to subject was higher than observed by most other workers. Day to day consistency within the same subject was rather low. Creatinine coefficient was computed per kg of body weight as well as per kg of lean body weight. In both the cases, it has been found to be higher in the males than in the females. Though an important factor, yet body weight of a subject alone could not explain satisfactorily wide variability of creatinine excretion in the present study. The possible influencing factors have been discussed along with clinical implications.
对84名健康医学生连续三天的每日尿肌酐排泄量和肌酐系数进行了研究。观察到男性受试者的每日肌酐排泄量高于女性受试者。观察到肌酐排泄量取决于受试者的体重。受试者之间的变异性高于大多数其他研究者的观察结果。同一受试者的每日一致性相当低。按每千克体重以及每千克瘦体重计算肌酐系数。在这两种情况下，均发现男性的肌酐系数高于女性。尽管体重是一个重要因素，但在本研究中，仅受试者的体重并不能令人满意地解释肌酐排泄的广泛变异性。文中讨论了可能的影响因素及其临床意义。
