Miller R G, Freund H J
Ann Neurol. 1980 Dec;8(6):574-9. doi: 10.1002/ana.410080605.
Patients with cerebellar lesions and limb ataxia performed two types of continuous tracking tasks involving flexion and extension of the index finger. In both tasks, patients were provided cutaneous and proprioceptive cues, but visual feedback was given in the first task (visual tracking) and not in the second (arbitrarily termed proprioceptive tracking). Raw records and Fourier-analyzed power spectra were compared with results in normal controls. Harmonic distortion was determined for each task. In all patients, as well as normal subjects, tracking performance was markedly improved and harmonic distortion substantially reduced during proprioceptive tracking. This surprising finding may result from a much shorter feedback loop for proprioceptive stimuli compared to visual stimuli. The tracking records, power spectra analysis, and determination of harmonic distortion provide both qualitative and quantitative data in patients with dyssynergia.
患有小脑病变和肢体共济失调的患者进行了两种涉及食指屈伸的连续跟踪任务。在这两项任务中，都为患者提供了皮肤感觉和本体感觉线索，但在第一项任务（视觉跟踪）中给予了视觉反馈，而在第二项任务（任意称为本体感觉跟踪）中未给予视觉反馈。将原始记录和经傅里叶分析的功率谱与正常对照组的结果进行了比较。确定了每项任务的谐波失真。在所有患者以及正常受试者中，本体感觉跟踪期间的跟踪性能均显著提高，谐波失真大幅降低。这一惊人发现可能是由于本体感觉刺激的反馈回路比视觉刺激的反馈回路短得多。跟踪记录、功率谱分析和谐波失真的测定为协同失调患者提供了定性和定量数据。
