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[鸽子过敏引起的肺炎。(I)。对流免疫电泳检测血清中特异性抗体的临床价值]

[Pneumonitis caused by hypersensitivity to pigeons. (I). Clinical value of counterimmunoelectrophoresis for detection of specific antibodies in the serum].

作者信息

Reyes P A, Sandoval J, Díaz de la Vega V

出版信息

Arch Inst Cardiol Mex. 1981 Jan-Feb;51(1):97-101.

PMID:7212863
Abstract

Hypersensitivity pneumonitis due to pigeon's exposure (pigeon's breeder disease) is a interstitial lung disease caused by immune mechanisms after sensitization to pigeon serum antigens. An immunological test, counterimmunoelectrophoresis (CIE), has been developed to recognize the humoral immune response against pigeon serum and dropping antigens, in a simple, low cost and fast test than other cumbersome tests presently in use. The CIE has high sensibility and specificity (X2 = 35.8 p 0.001) that guarantee its clinical usefulness. When Pigeon breeder's disease is suspected on clinical grounds, the CIE test is indicated to confirm diagnosis.

摘要

因接触鸽子引起的超敏性肺炎(鸽饲养者病)是一种间质性肺病,由对鸽血清抗原致敏后的免疫机制所致。一种免疫检测方法——对流免疫电泳(CIE)已被开发出来,用于识别针对鸽血清和鸽粪抗原的体液免疫反应,该方法简单、成本低且快速,比目前使用的其他繁琐检测方法更具优势。CIE具有高敏感性和特异性(X2 = 35.8,p < 0.001),这保证了其临床实用性。当基于临床理由怀疑患有鸽饲养者病时,建议进行CIE检测以确诊。

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