Rushton J G, Stevens J C, Miller R H
Arch Neurol. 1981 Apr;38(4):201-5. doi: 10.1001/archneur.1981.00510040027002.
In 217 cases of glossopharyngeal neuralgia seen at the Mayo Clinic between 1922 and 1977, the disease was more common in patients older than 50 years (57%), but also occurred in 43% who were between 18 and 50. Spontaneous remissions were noted by 161 patients, but 37 had no periods of pain relief. Syncope was rarely a problem. Involvement was bilateral in 12%. The combination of glossopharyngeal and trigeminal neuralgia was found in 25 patients. Positive results on the cocaine test in 112 of 125 patients aided in diagnosis. Carbamazepine is the favored medication. Early surgical experience consisted of extracranial avulsion of the glossopharyngeal nerve or intracranial section at the jugular foramen; since 1948, surgical treatment has included section of the glossopharyngeal nerve and usually the upper rootlets of the vagus nerve and additional section of the fifth cranial nerve when trigeminal neuralgia was associated. Good relief of pain was obtained surgically in 110 patients.
1922年至1977年间在梅奥诊所诊治的217例舌咽神经痛患者中，该病在50岁以上患者中更为常见（57%），但18至50岁患者中也有43%发病。161例患者出现自发缓解，但37例患者无疼痛缓解期。晕厥很少成为问题。12%的患者双侧受累。25例患者同时患有舌咽神经痛和三叉神经痛。125例患者中有112例可卡因试验结果阳性，有助于诊断。卡马西平是首选药物。早期手术经验包括舌咽神经颅外撕脱术或在颈静脉孔处进行颅内切断术；自1948年以来，手术治疗包括切断舌咽神经，通常还切断迷走上根，当伴有三叉神经痛时还额外切断第五颅神经。110例患者通过手术获得了良好的疼痛缓解。
