Howe A, Nicholson A N
Aviat Space Environ Med. 1981 Jan;52(1):11-5.
Adaptation to denervation of the carotid sinus region was studied on cats during hypotension induced by a controlled haemorrhage. After denervation, the fall in arterial pressure in response to haemorrhage was increased, but rhe partial recovery of blood pressure was preserved. In chronic animals, this pattern of response was also seen, but a resting hypertension developed and ensured that the minimal blood pressure and the recovery reached during the haemorrhage were similar to those of intact animals. The studies suggest that the primary role of the carotid receptors is to minimize the effect of stresses which lead to hypotension, rather than to set the level of the resting blood pressure.
在控制性出血诱导的低血压期间，对猫的颈动脉窦区域去神经支配后的适应性进行了研究。去神经支配后，对出血的动脉血压下降增加，但血压仍有部分恢复。在慢性动物中也观察到这种反应模式，但出现了静息性高血压，确保了出血期间达到的最低血压和恢复情况与完整动物相似。这些研究表明，颈动脉感受器的主要作用是将导致低血压的应激影响降至最低，而不是设定静息血压水平。
