Proshliakova E V, Mitskevich M S, Rumiantseva O N
Biull Eksp Biol Med. 1981;91(1):71-3.
Triiodothyronine (T3) and thyroxin (T4) were detected by radioimmunoassay in the thyroid gland and serum of encephalectomized and intact rabbit fetuses. Encephalectomy performed on the 22-23d day of development did not produce any effect on thyroid hormone concentrations in 29-day-old fetuses. However, on the 30th day the concentrations of T2 and T4 in the thyroid gland were significantly lower in the encephalectomized fetuses than in the intact ones. These findings were consistent with changes in the morphological structure of the thyroid gland. The results obtained indicate that the hypothalamus begins to control thyroid function in the rabbit fetuses apparently from the 30th day of prenatal life.
采用放射免疫分析法检测了去脑和完整兔胎儿甲状腺及血清中的三碘甲状腺原氨酸（T3）和甲状腺素（T4）。在发育第22 - 23天进行去脑手术，对29日龄胎儿的甲状腺激素浓度未产生任何影响。然而，在第30天，去脑胎儿甲状腺中T2和T4的浓度显著低于完整胎儿。这些发现与甲状腺形态结构的变化一致。所得结果表明，下丘脑显然从胎儿出生前第30天开始控制兔胎儿的甲状腺功能。
